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Deep down I believe he does but he does his best to hide it.  Once he commits the murder he falls apart and has to be ordered around by his wife.  She calls him "infirm of purpose" as he refuses to return to the room as "he dares not look" at the sin he has commited.  This then causes him to further murder others in a bid to keep hold of the power he has obtained. If he were to lose his kingship then he would be faced with his sin of regicide which would clearly have no purpose other than his empty ambition.  While he is king he can justify his actions as necessary and not his fault.

I would argue that he becomes resigned to what he did and in the last Tomorrow speech he feels some regret I feel for the waste his life became. Macbeth broke the enterprise to his wife, she pushes him toward it - some suggest (and I agree) that the Macbeth have lost a child and Lady Macbeth is looking to her husband for greatness as a substitute for a mother looking toward a child. However Macbeth does not really feel sorrow for Duncan, no.

He was ambitious and was pushed into the King's murder by Lady Macbeth.  He felt a little remorse looking at the sleeping King, but he still murdered him. He felt horror at what he had done which affected his mind.  His justification was the witches prophecy and so therefore could have altered his perception into thinking he wasn't responsible and therefore King Duncan had to die! 

No There is no body who knows what is going to happen in a battle.At the crowdy civil war where and when king Duncan died  it was time to fulfill the prophecy. He had to  die because it had reached Macbeth's time to rule .

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