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cell mediated response is effectuated by mostly T cells and other cells such as Natural Killer cells.

Humoral response on the other hand is mediated by antibodies produced by B cells (plasma cells to be more specific)


Differences: Humoral immunity is dependent on antibodies produced by plasma cells while CMI relies on cytotoxic T-lymphocytes. Humoral immunity is directed mainly against extra-celluar antigens, such as a bacteria. Humoral responses are MHC-II restricted, while CMI is MHC-I restricted. 
Similarities: Both responses are specific for a particular antigen, both result in long-term memory, both rely on lymphocytes.

Hi there!

They are both a type of specific immune response: i.e  they involce a generation of specialised lymphocytes against a specific antigen.

Humoral immunity is the antibody mediated cell response. Very briefly: B cells recognise antigens then proliferate into plasma cells (which produce antibodies) and memory type B cells.

The cell mediated response is mainly mediated by T cells. This involves self cells that display a MHC protein (eg virus infected cells) T cells proliferate into cytotoxic t cells which destroy the abnormal cells and may induce b cells to make antibodies.

Hope that helps :) if you have any more questions on any bio topic feel free to message me!

okay, does is stand for anything?

the MHC receptors are responsible for rejecting any foreign material or accepting them for example skin grafts

thanks, what is MHC receptors?

they are both a form of specific immune response

The hum oral response involves b cells that recognise antigens or pathogens that circulate in the lymph and blood. The cell mediated response involves mostly T cells and responds to any cell that displays MHC receptors, including cells invaded by pathogens, tumour cells or transplanted cells

Humoral Immunity 

1. It consists of B-lymphocytes which produce the antibodies that circulate in the body fluids.

2. It defends the body against viruses and bacteria.

3. It does not respond to transplants.

4. It does not provide immunity against cancer.

Cell Mediated Immunity 

1. It consists of T-lymphocytes which produce normally 4 types of T-cells.

2. It defends the body against all pathogens including fungi and protozoa.

3. It reacts against transplants.

4. It provides immunity against cancer.

NB: yes they are both specific immune response 

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